De legendarische half-vampier, half-menselijke vampierjager Blade volgt Deacon Frost, een zeer machtige en invloedrijke vampier die zijn moeder heeft vermoord en die leiding geeft aan Existence, een geheimzinnige vampierorganisatie die actief is in Zuidoost-Azië.
| Production | Cort Lane | Producer |
| Production | Fuminori Hara | Producer |
| Production | Taro Morishima | Producer |
| Sound | Reiji Kitasato | Music |
| Sound | Shogo Ohnishi | Music |
| Sound | Tetsuya Takahashi | Music |
| Camera | Yuki Kawashita | Director of Photography |
| Writing | Marv Wolfman | Characters |
| Writing | Gene Colan | Characters |
| Sound | Toshihiko Nakajima | Sound Director |
| Visual Effects | Cindy H. Yamauchi | Character Designer |
| Writing | Warren Ellis | Story |
| Production | Jeph Loeb | Executive Producer |
| Production | Alan Fine | Executive Producer |
| Production | Dan Buckley | Executive Producer |
| Production | Eric S. Rollman | Executive Producer |
| Production | Simon Philips | Executive Producer |
| Production | Joe Quesada | Co-Executive Producer |
| Production | Stan Lee | Co-Executive Producer |
| Production | Masao Takiyama | Executive Producer |
| Production | Megan Thomas Bradner | Associate Producer |
