Een Amerikaanse satelliet stort neer in de buurt van een klein stadje in Utah, waardoor een dodelijke plaag ontstaat die vrijwel iedereen doodt, behalve twee overlevenden, die aanwijzingen kunnen geven voor het immuniseren van de bevolking. Terwijl het leger probeert het gebied in quarantaine te plaatsen, wordt een team van zeer gespecialiseerde wetenschappers samengesteld om een geneesmiddel te vinden en de verspreiding van de buitenaardse ziekteverwekker, met de codenaam Andromeda, te stoppen.
 | Seizoen 1 Aflevering 1 Part 1 Datum: 2008-05-26 Lengte: 120 min |
 | Seizoen 1 Aflevering 2 Part 2 Datum: 2008-05-27 Lengte: 120 min |
| Production | Mikael Salomon | Producer |
| Production | Ridley Scott | Executive Producer |
| Production | David W. Zucker | Executive Producer |
| Production | Clara George | Producer |
| Production | Tom Thayer | Executive Producer |
| Production | Tony Scott | Executive Producer |
| Production | Denise Chamian | Casting |
| Costume & Make-Up | Karin Nosella | Costume Coordinator |
| Art | Roger Jacoe | Lead Painter |
| Sound | Richard Steele | Sound Designer |
| Directing | Patti Henderson | Script Supervisor |
| Sound | Bill Bell | Sound Editor |
| Camera | Russell Hawkes | Dolly Grip |
| Camera | Ryan Monro | Dolly Grip |
| Art | Merlin Dervisevic | Set Decoration |
| Sound | Bob Costanza | Sound Editor |
| Art | Jerry Wanek | Production Design |
| Production | Ron Binkowski | Co-Producer |
| Sound | Daniel Tripoli | Sound Editor |
| Art | Dean Eilertson | Property Master |
| Camera | Marty McInally | Camera Operator |
| Sound | G. Michael Graham | Supervising Sound Editor |
| Sound | Terry O'Bright | Sound Re-Recording Mixer |
| Camera | Simon Jori | First Assistant Camera |
| Sound | Bunny Andrews | Music Editor |
| Art | Dan Hermansen | Art Direction |
| Costume & Make-Up | Jill Bailey | Makeup Artist |
| Costume & Make-Up | Ian C. Ballard | Key Hair Stylist |
| Art | Josephine Bleuer | Greensman |
| Art | Adrian Hrytzak | Art Department Coordinator |
| Sound | Keith Rogers | Sound Re-Recording Mixer |
| Lighting | Keith Woods | Rigging Gaffer |
| Costume & Make-Up | Paul Lavigne | Wardrobe Supervisor |
| Editing | Jessica Schulte | Assistant Editor |
| Production | Bruce L. Brownstein | Location Manager |
| Editing | Scott Vickrey | Editor |
| Production | Malcolm Reeve | Co-Producer |
| Crew | Nicholas Podbrey | Makeup Effects |
| Camera | Jim Filippone | Helicopter Camera |
| Costume & Make-Up | Connie Parker | Makeup Department Head |
| Crew | Dave Hospes | Stunt Coordinator |
| Camera | Jon Joffin | Director of Photography |
| Production | Scout Masterson | Casting |
| Costume & Make-Up | Jenni Gullett | Costume Design |
| Production | Julia Neville | Production Manager |
| Directing | Ken Shane | First Assistant Director |
| Sound | Erich Gann | Sound Effects Editor |
| Camera | John Kuchera | Key Grip |
| Lighting | Mike Kolafa | Gaffer |
| Directing | Crystal Braunwarth | Script Coordinator |
| Art | Glenn Woodruff | Construction Coordinator |
| Sound | Tim Terusa | Sound Editor |
| Crew | Tony Lazarowich | Special Effects Coordinator |
| Art | Vicky Peters | Set Designer |
| Sound | Robert McDonagh | Boom Operator |
| Visual Effects | Jan Vseticek | Visual Effects Coordinator |
| Editing | Josh Beal | Assistant Editor |
| Production | Adrienne Sol | Production Coordinator |
| Crew | Ryan Steacy | Armorer |
| Costume & Make-Up | Susan Boyd | Hairstylist |
| Sound | Devon Heffley Curry | Supervising ADR Editor |
| Sound | Mike Dickeson | Sound Editor |
| Sound | Anton Holden | Sound Editor |
| Visual Effects | David Váňa | Visual Effects Supervisor |
| Camera | Pascal Jean Provost | Camera Operator |
| Sound | Joel J. Richard | Original Music Composer |
| Writing | Robert Schenkkan | Screenplay |
| Crew | Doug Chapman | Stunts |
| Writing | Michael Crichton | Novel |
